Infosys, a global leader in AI–first business consulting and technology services, announced its strategic collaboration with Sentara, a leading not–for–profit healthcare organization, to create a scalable foundation for AI–driven transformation that aims to enhance efficiency, support clinicians and staff, and improve experiences for patients and members.

As part of its AI-first approach, Infosys is leveraging Infosys Topaz Fabric, a purpose-built agentic services suite, which unifies infrastructure, models, data, applications and workflows into a composable, agent-ready ecosystem, spanning AI strategy and road–mapping. The framework will allow Sentara to reference architectures, AI–first SDLC modernization and govern scaling to embed AI across core hospital and enterprise workflows. This vision includes aligning AI initiatives to real–world healthcare priorities spanning care management, employee productivity and digital front–office experiences.

The collaboration emphasizes responsible AI design, enterprise guardrails and operational readiness enabling AI to move from experimentation to production across healthcare systems. This approach will enable Sentara to prioritize high–value use cases, scale successful pilots and evolve AI capabilities across business operations and IT in line with the organization's strategic goals and regulatory considerations. By embedding AI within day–to–day workflows, the initiative aims to help Sentara operate with greater speed, consistency and resilience while maintaining a strong focus on patient and caregiver experience. The collaboration focuses on building trust in AI, enabling responsible adoption and delivering measurable value across clinical, operational and digital domains.

Jamisson Fowler, SVP and Chief Digital Officer, Sentara, said, "As we continue to advance our digital strategy, working with Infosys enables us to take a thoughtful and scalable approach to AI adoption across the enterprise. This collaboration helps ensure AI is deployed in ways that genuinely improve how our hospital teams work supporting efficiency, care delivery and the communities we serve while remaining secure, compliant and patient–centered."

Venky Ananth, EVP and Global Head, Healthcare, Infosys, said, "Healthcare organizations are at a pivotal moment where AI can meaningfully enhance clinical and operational outcomes when it is adopted responsibly and at scale. Our collaboration with Sentara is focused on unlocking AI value by building a strong enterprise AI foundation spanning architecture, governance and AI–first delivery models so that innovation is operationalized across hospital systems and translates into real efficiency gains for clinicians, staff and patients."